A landmark research paper on why keeping weight off is so much harder than losing it: after weight loss the body burns fewer calories and ramps up hunger to pull the weight back on. It is biology, not a lack of willpower.
Read on!An expert workshop report on why preventing regain is the hardest part of weight loss: after losing weight, both appetite and metabolism adapt to pull you back. Here's what the science says.
Read on!A landmark study showing that after weight loss, your appetite hormones shift to drive regain - and those changes are still there a year later. It's biology, not willpower.
Read on!Six years after the competition, contestants had regained much of the weight - and their metabolisms were still burning hundreds of calories a day less than expected. A landmark look at lasting metabolic adaptation.
Read on!A review proposing that everyday environmental chemicals - in air, food, packaging, and household products - disrupt hormones and metabolism in ways that promote weight gain, alongside diet and lifestyle.
Read on!A foundational review showing you don't need to reach an "ideal" weight to get healthier - a modest 5-10% loss meaningfully improves blood sugar, blood pressure, and cholesterol.
Read on!A study measuring body composition across the menopause transition: postmenopausal women had less muscle and more belly fat across every weight category - and the shift was most striking in "normal-weight" women.
Read on!A trial found that choosing weight medication based on a person's "phenotype" - the main driver of their eating - nearly doubled weight loss (about 16% vs. 9% at a year).
Read on!A deep review on "redox" biology - the balance of oxidation in your cells - and how it goes off-kilter in obesity, metabolic syndrome, and diabetes. Why oxidative stress and metabolism are inseparable.
Read on!In postmenopausal women on semaglutide, those also using menopause hormone therapy lost more weight (about 16% vs. 12% at a year). An early signal that hormones and weight meds may work together.
Read on!The full scientific report behind the "planetary health diet": how the world can feed everyone healthy food within environmental limits - and why food systems sit at the center of health, climate, and fairness.
Read on!A review of why midlife women gain weight and shift fat to the middle - it's aging plus menopause hormones plus lifestyle - and what actually helps prevent and manage it.
Read on!A medical review of why postmenopausal women are especially affected by obesity - the hormonal and lifestyle drivers, the health risks, and the full range of evidence-based treatments.
Read on!